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KMID : 0361620120470020156
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Journal of the Korean Orthopaedic Association
2012 Volume.47 No. 2 p.156 ~ p.159
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A Medication for Newly Diagnosed Rheumatoid Arthritis in Patient with Lactose Intolerance
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Son Jung-Hwan
Lee Gun-Woo
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Abstract
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The side effects of rheumatoid arthritis (RA) medication, such as irritation and ulceration of the gastrointestinal mucosa, have been observed and many patients fi nd it diffi cult to swallow tablets and hard gelatin capsules. This results in a high incidence of noncompliance and ineffective therapy towards treating RA. Fast-dissolving and fast-dispersing drug delivery systems may offer a solution to these problems, and as a result, fast disintegrating tablets are gaining prominence as a new drug-delivery system; one such system is the binding of the active ingredient with lactose. There have been no reports on the rate of lactose intolerance against medication in patients with newly diagnosed RA, because lactose intolerance has not been associated with particular problems with most existing RA therapies. We encounterd a 56-year-old lactose intolerant female patient who had severe diarrhea after receiving drugs to treat her newly diagnosed RA.
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KEYWORD
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lactose intolerance, rheumatoid arthritis
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